Comprehensive studies of ligand-gated receptors depend on reliable, accurate and repetitive responses of said receptors to the co-application of agonists. If a liquid exchange is not precise and complete, receptor desensitization will ultimately act as the limiting factor in an assay.
What is discussed:
Data will be presented showing how the new flow control technology implemented in IonFlux Mercury can enhance existing ligand-gated assays (Nicotinic and GABA receptors) limiting receptor desensitization and increasing reproducibility of currents.
