Lung Biofilms
Bacterial and fungal biofilms are a major factor in many pulmonary diseases and infections. Lung inflammation can range from pneumonia biofilm development to chronic infection from Pseudomonas aeruginosa in cystic fibrosis patients. These pathogens have the capabilities to invade the entire respiratory system.
With the BioFlux system, analysis of these biofilms is made easy. Customers have used the BioFlux for a wide array of lung biofilm assays, including the competition between bacterial strains and the discovery of novel anti-biofilm drugs.
Key BioFlux Advantages For Lung Biofilm Studies
- Controlled, continuous flow provides a perfect environment for anti-biofilm drug discovery for treatment of pulmonary diseases such as cystic fibrosis
- Multiple channels allows for comparison and/or competition between biofilms isolated from patients
- A precise validation tool for in vivo assays with the ability to visualize events occurring in the lungs
- Several shear flow rates can be utilized to replicate pressure in the respiratory system for different infections
