Vascular thrombosis is a serious health issue that can cause heart attack, ischemic stroke, or death. Current clot-busting treatments, including the administration of heparin, are plagued by deleterious side effects, such as uncontrolled bleeding. Investigators at Children’s Hospital of Philadelphia are examining the modification of IgG antibodies as a potential alternative therapeutic intervention. In this webinar, Dr. Amrita Sarkar will discuss IgG modification and the use of shear flow for thrombosis treatment characterization.
Dr. Sarkar will share insights on:
1. Heparin-induced thrombocytopenia
2. KKO antibody modification
3. In vitro & in vivo modified KKO efficacy
