Hematology Applications
Thrombosis, Platelet Activity, and Atherosclerosis Models
The BioFlux system is particularly suited the leading platform for studying platelet function in vitro. Platelet aggregation and adhesion inhibition can be quantitated under controlled shear, providing major advantages over traditional adhesion assays.
The BioFlux system enables simulation of vasculature shear rates up to 200 dyne/cm2 (5000 s-1) using whole blood, platelet-rich plasma or other cells of interest. Experiments can be run on purified matrix proteins (von Willebrand factor, collagen, etc.) or endothelial cell monolayers. The system uses as little as 20μL of blood per experiment.
Sickle Cell Disease
Investigate adhesive properties of sickle erythrocytes in a simulated blood flow environment
Stem Cells
Investigate stem cell function under flow: homing, adhesion, transmigration, and differentiation.