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Publication: Fatty-Acid Uptake in Prostate Cancer Cells Using Dynamic Microfluidic Raman Technology

In this investigation, Tang et al. used a BioFlux Shear Flow System to examine the impact of fatty acid uptake by prostate cancer cells in real-time. The group found that prostate cancer cells take up fatty acids under shear stress and that omega-3 fatty acids docosahexaenoic acid and eicosapentaenoic acid reduced fatty acid uptake. This reduction was observable by Raman spectroscopy while the cells were under shear flow conditions. In line with previous findings, the group also found that fatty acid uptake was increased during hypoxia.

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