Mitigate contamination issues of shear flow experiments
This blog highlights the real-world benefits of the BioFlux system’s contactless pumping to the lab of Dr. Clemence Belleannee of the University of Laval.
Anson Blanks
Dr. Anson Blanks completed his BS in exercise physiology at East Carolina University and his MS in clinical exercise science at Appalachian State University. After working as a clinical exercise physiologist in cardiopulmonary rehabilitation, Dr. Blanks decided to pursue a career in scientific research. He attended Virginia Commonwealth University, where he completed his Ph.D. in Rehabilitation and Movement Science. After spending several years as a research and development scientist in biotechnology industry, Dr. Blanks is now a scientific marketing manager for Cell Microsystems in Durham, NC.
DIY breakdown: Advantages and Disadvantages of Do-it-yourself Flow Systems
Mechanical forces have been shown to impact cell phenotype and function in vivo. The most prolific of these forces is shear stress, induced by fluid movement throughout the body. Shear stress has been demonstrated to impact polarization, alignment, differentiation, and function of various cell types, including endothelial cells, leukocytes, and stem cells. Despite the impact […]
The Power of Shear Flow: 5 Innovative Publications Investigating Microbial Threats
Bacterial biofilms are found throughout nature, in places such as ponds, the human body, and food. Although humans peacefully co-exist and even benefit from many types of bacteria, some strains, such as Pseudomonas aeruginosa, can form pathogenic biofilms. To combat these harmful biofilms, many researchers are engaged in investigations aimed at determining the mechanisms of […]
Tech Talk: Enhancing Microbiology Investigations
Many infections in humans, including medical device infections, chronic wounds, staph skin infections, and endocarditis, involve biofilms (1). Troublingly, due to their protective matrix, many biofilms can evade the immune system and may have an inadequate response to antibiotic treatment. This can lead to chronic infections and antimicrobial resistance. Therefore, the development of effective prevention […]
Advances in Biofilm Research: How the Experts are Overcoming Obstacles
Recently, some members of the Cell Microsystems team traveled to the United Kingdom, to speak with researchers at some of the institutions associated with the National Biofilms Innovation Center (NBIC). While there, our team was fortunate to speak with several microbiologists who were conducting investigations in two major areas: biofilm drug resistance and antibiofilm drug […]
The Evolution of Polymicrobial Assessment: From Culture to Automation
The study of biofilm communities presents unique challenges in experimental design and analysis. While mixed bacterial populations offer fascinating insights into microbial interactions and community dynamics, accurately characterizing and investigating these complex systems has previously required sophisticated and tedious technical approaches. Here, we will discuss advances in technology that have helped to simplify and streamline […]
From Milliliters to Microliters: How a Shear Flow System Can Reduce Sample Requirements for Experiments
Imagine working with a rare patient-derived cell samples. In a traditional setup, you might need 1 milliliter of sample (equivalent to about 20 drops) to run an experiment. With a microfluidic system, you could potentially get the same results with just 10 microliters (about one-half of a single drop). This efficiency opens up entirely new […]
Unlocking the Secrets of Antibiotic Resistance: How Shear Flow Systems Are Revolutionizing the Fight Against Superbugs
In the ongoing battle against antibiotic-resistant bacteria, or “superbugs,” scientists are constantly seeking innovative tools to understand the mechanisms of resistance and develop effective treatments. One such groundbreaking technology is shear flow systems, which have emerged as game-changers in microbiological research. By simulating the dynamic conditions of bacteria’s natural environments, such as the human body […]